Application of continuous substrate feeding to the ABE fermentation: relief of product inhibition using extraction, perstraction, stripping, and pervaporation
|Title||Application of continuous substrate feeding to the ABE fermentation: relief of product inhibition using extraction, perstraction, stripping, and pervaporation|
|Publication Type||Journal Article|
|Year of Publication||1992|
|Authors||Qureshi N, Maddox I, Friedl A|
The technique of continuous substrate feeding has been applied to the batch fermentation process using freely suspended cells, for ABE (acetone-butanol-ethanol) production. To avoid the product inhibition which normally restricts ABE production to less than 20 g/L and sugar utilization to 60 g/L, a product removal technique has been integrated into the fermentation process. The techniques investigated were liquid-liquid extraction, perstraction, gas-stripping, and pervaporation. By using a substrate of whey permeate, the reactor productivity has been improved over that observed in a traditional batch fermentation, while equivalent lactose utilization and ABE production values of 180 g and 69 g, respectlvely, have been achieved in a 1-L culture volume.